The call to adventure is felt by many and general practice is a career that can take you there! As GPs grow their portfolios, they look for interesting and unusual ways to forge their own paths. This can take them all round the world (and back again). In the first episode in a two-part series, Drs James and Rebecca Waldron discuss adventure and expedition medicine, finding inspiration and opportunities, preparing oneself and getting started on the journey. Rebecca recently returned from a 3-month voyage with the marine conservation charity Sea Shepherd. As the boat's medic, she tended to crew members' daily illnesses, performed infection control during a COVID outbreak, and provided emotional support. In their conversation, James and Rebecca consider how such expeditions provide an opportunity for career diversification for primary care professionals.